Table 5. Adjusted Cox Proportional Hazards Analysis of MACCE and All-Cause Mortality in Relation to Cardiac MRI-Derived RVMI, RV ESVI, and RVEF.
Parameter | MACCE | All-Cause Mortality | |||||
---|---|---|---|---|---|---|---|
HR | 95% CI | P | HR | 95% CI | P | ||
Systolic RVMI, per increase of 5 g/m2 | |||||||
Univariable | 1.34 | 1.08–1.65 | 0.009 | 1.75 | 1.34–2.29 | < 0.001 | |
Age and sex adjusted | 1.44 | 1.13–1.86 | 0.004 | 1.87 | 1.33–2.62 | < 0.001 | |
Age, sex, and TR jet area adjusted | 1.30 | 0.97–1.75 | 0.09 | 1.96 | 1.30–2.94 | < 0.001 | |
Age, sex, TR jet area, and dialysis adjusted | 1.28 | 0.94–1.73 | 0.11 | 2.01 | 1.28–3.16 | 0.002 | |
RV ESVI, per increase of 10 mL/m2 | |||||||
Univariable | 1.04 | 0.97–1.12 | 0.27 | 1.10 | 1.01–1.20 | 0.03 | |
Age and sex adjusted | 1.06 | 0.98–1.15 | 0.15 | 1.09 | 0.98–1.21 | 0.10 | |
Age, sex, and TR jet area adjusted | 0.95 | 0.84–1.07 | 0.41 | 1.15 | 0.90–1.23 | 0.56 | |
Age, sex, TR jet area, and dialysis adjusted | 0.95 | 0.84–1.07 | 0.40 | 1.03 | 0.88–1.22 | 0.69 | |
RVEF, per increase of 5% | |||||||
Univariable | 0.93 | 0.79–1.08 | 0.33 | 0.82 | 0.66–1.03 | 0.09 | |
Age and sex adjusted | 0.89 | 0.75–1.07 | 0.22 | 0.86 | 0.67–1.11 | 0.26 | |
Age, sex, and TR jet area adjusted | 0.94 | 0.79–1.11 | 0.46 | 0.89 | 0.69–1.16 | 0.40 | |
Age, sex, TR jet area, and dialysis adjusted | 0.94 | 0.79–1.12 | 0.47 | 0.92 | 0.71–1.20 | 0.54 |
CI = confidence interval, EF = ejection fraction, ESVI = end-systolic volume index, HR = hazard ratio, MACCE = major adverse cardiac and cerebrovascular event, MI = mass index, RV = right ventricle, TR = tricuspid regurgitation