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. Author manuscript; available in PMC: 2021 Jul 28.
Published in final edited form as: Mov Disord. 2020 May 1;35(8):1388–1395. doi: 10.1002/mds.28060

TABLE 1.

Demographics and clinical data

PD MSAp PSP
Sample size 38 17 16
Age, y 64.84 (9.03) 67.71 (9.12) 70.94 (7.77)
Sex, male/female 29/9 12/5 7/9
Disease duration, mos. 48.13 (29.44) 55.47 (35.39) 35.94 (32.14)
Total LEDD 693.32 (259.09)b,c 448.82 (570.93)a 429.69 (364.83)a
Hoehn & Yahr stage 1.92 (0.49)b,c 3.35 (1.00)a,c 3.06 (1.18)a,b
MDS-UPDRS III 28.13 (11.88)b,c 44.53 (14.45)a 41.81 (13.87)a
MoCA 25.50 (2.87)b,c 21.18 (4.73)a 21.19 (5.38)a
NfL 13.30 (6.29)b,c 27.08 (17.81)a 26.05 (14.88)a
MRPI 10.66 (2.60)c 10.85 (4.90)c 18.77 (7.01)a,b

Abbreviations: PD, Parkinson’s disease; MSAp, multiple system atrophy parkinsonian variant; PSP, progressive supranuclear palsy; LEDD, levodopa equivalent daily dose; MDS-UPDRS III, Part III of the Movement Disorders Society Unified Parkinson’s Disease Rating Scale; MoCA, Montreal Cognitive Assessment; NfL, neurofilament light chain protein; MRPI, Magnetic Resonance Parkinsonism Index.

a

P < 0.05 versus PD.

b

P < 0.05 versus MSAp.

c

P < 0.05 versus PSP.