TABLE 1.
PD | MSAp | PSP | |
---|---|---|---|
Sample size | 38 | 17 | 16 |
Age, y | 64.84 (9.03) | 67.71 (9.12) | 70.94 (7.77) |
Sex, male/female | 29/9 | 12/5 | 7/9 |
Disease duration, mos. | 48.13 (29.44) | 55.47 (35.39) | 35.94 (32.14) |
Total LEDD | 693.32 (259.09)b,c | 448.82 (570.93)a | 429.69 (364.83)a |
Hoehn & Yahr stage | 1.92 (0.49)b,c | 3.35 (1.00)a,c | 3.06 (1.18)a,b |
MDS-UPDRS III | 28.13 (11.88)b,c | 44.53 (14.45)a | 41.81 (13.87)a |
MoCA | 25.50 (2.87)b,c | 21.18 (4.73)a | 21.19 (5.38)a |
NfL | 13.30 (6.29)b,c | 27.08 (17.81)a | 26.05 (14.88)a |
MRPI | 10.66 (2.60)c | 10.85 (4.90)c | 18.77 (7.01)a,b |
Abbreviations: PD, Parkinson’s disease; MSAp, multiple system atrophy parkinsonian variant; PSP, progressive supranuclear palsy; LEDD, levodopa equivalent daily dose; MDS-UPDRS III, Part III of the Movement Disorders Society Unified Parkinson’s Disease Rating Scale; MoCA, Montreal Cognitive Assessment; NfL, neurofilament light chain protein; MRPI, Magnetic Resonance Parkinsonism Index.
P < 0.05 versus PD.
P < 0.05 versus MSAp.
P < 0.05 versus PSP.