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. 2021 Jul 14;12:698981. doi: 10.3389/fphar.2021.698981

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Copyright © 2021 Jia, Cao, Li, Gan, Li, Lan, Meng, He, Zhang, Wang and Yuan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Functional analysis of candidate targets. (A) Top 20 of biological process enrichment. Results showed that the candidate targets involved in a variety of biological processes, such as steroid hormone receptor activity, nuclear receptor activity, transcription factor activity, director ligand regulated sequence-specific binding. (B) Top 20 of pathway enrichment. Molecular signaling pathways of XTN were highlighted, such as PI3K-AKt signaling pathway, MAPK signaling pathway, Ras signaling pathway, Rap1 signaling pathway.