Table 4.
Physiological and ventilator parameters in survivors and non-survivors
| Survivors | Non-survivors | p value | |
|---|---|---|---|
| SOFA | 8 (5–13) | 11 (8–13) | 0.241 |
| P/F ratio 1 day before MPSa (mmHg) | 156 (140–187) | 122 (83–153) | 0.119 |
| P/F ratio 3 days after MPS (mmHg) | 182 (156–221) | 113 (99–187) | 0.091 |
| P/F ratio 1 day before CYC (mmHg) | 129 (98–166) | 113 (80–131) | 0.214 |
| P/F ratio 3 days after CYC (mmHg) | 220 (159–270) | 114 (69–207) | 0.079 |
| Cdyn 1 day before MPS (mL/cmH2O) | 59 (34–87) | 20 (17–42) | 0.111 |
| Cdyn 3 days after MPS (mL/cmH2O) | 63 (51–91) | 27 (14–61) | 0.077 |
| Cdyn 1 day before CYC (mL/cmH2O) | 75 (41–126) | 27 (8–63) | 0.442 |
| Cdyn 3 days after CYC (mL/cmH2O) | 92 (52–151) | 20 (9–36) | 0.063 |
Values are expressed as median and interquartile range (IQR)
CYC, cyclophosphamide; Cdyn, dynamic compliance; MPS, methylprednisolone; P/F ratio, PaO2/FiO2-ratio; SOFA, Sequential Organ Failure Assessment;
aMethylprednisolone 1 g/day for 3 days