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. 2021 Jul 21;27(27):4453–4467. doi: 10.3748/wjg.v27.i27.4453

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©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/

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Progression-free survival according to plasma angiogenesis marker level. A: Angiopoietin-1; B: Angiopoietin-2; C: Vascular endothelial growth factor; D: Alpha-fetoprotein. AFP: Alpha-fetoprotein; Ang-1: Angiopoietin-1; Ang-2: Angiopoietin-2; VEGF: Vascular endothelial growth factor; HR: Hazard ratio; CI: Confidence interval.