Table 4. Twelve possible scenarios for a clinical example (BD = 6 mm, DT = 2 mm, and apical height = 4 mm in 16 mm COMS plaques) and corresponding estimated ODDs.

BD: basal dimension, DT: tumor margin-to-optic disc distance, COMS: Collaborative Ocular Melanoma Study, ODD: optic disc dose.

Scenario #	Seed type	COMS plaque-type	Prescription depth (mm)	Dose conversion factor relative to the depth of 5 mm	Estimated ODD (Gy)	Absolute dose reduction from standard plaque (Gy)	Relative dose reduction from standard plaque (%)	Reference
1	125I	Standard	5	1.00	190.43	Unavailable	Unavailable	Figure 3(d)
2	125I	Notched with one seed removed	5	1.00	131.52	58.91	30.94	Figure 4(c)
3	125I	Notched with two seeds removed	5	1.00	96.71	93.72	49.21	Figure 5(b)
4	103Pd	Standard	5	1.00	195.48	Unavailable	Unavailable	Figure 3(d)
5	103Pd	Notched with one seed removed	5	1.00	131.89	63.59	32.53	Figure 4(c)
6	103Pd	Notched with two seeds removed	5	1.00	93.27	102.21	52.29	Figure 5(b)
7	125I	Standard	4	0.81	154.25	Unavailable	Unavailable	Figure 3(d) and Table 1
8	125I	Notched with one seed removed	4	0.81	106.53	47.72	30.94	Figure 4(c) and Table 2
9	125I	Notched with two seeds removed	4	0.81	78.34	75.91	49.21	Figure 5(b) and Table 3
10	103Pd	Standard	4	0.80	156.38	Unavailable	Unavailable	Figure 3(d) and Table 1
11	103Pd	Notched with one seed removed	4	0.79	104.19	52.19	33.37	Figure 4(c) and Table 2
12	103Pd	Notched with two seeds removed	4	0.79	73.68	82.70	52.88	Figure 5(b) and Table 4