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. Author manuscript; available in PMC: 2021 Jul 28.
Published in final edited form as: J Cancer Res Clin Oncol. 2019 Apr 2;145(6):1437–1448. doi: 10.1007/s00432-019-02909-z

Fig. 4.

Fig. 4

Human Primary B cells isolated from human tonsil. a Expression of Rel-A, Rel-B, cRel, NFkB1/p105, p50, NFkB2/p100 and p52 proteins in naïve B cells (NBC), centroblasts (CB) and centrocytes (CC) was determined via western blotting. b Single-locus ChIP showed both Rel-B and cRel enrichment on CDK6 and CCND3 promoters. Error bars mean SD. Three independent experiments were performed. This is a representative assay. c Qt-PCR showed enhanced CDK6 and CCND3 mRNA expression in centroblasts compared to that in naïve B cells and centrocytes. Regarding BCL2 mRNA the lowest level was found in centroblasts. Error bars mean SD. Three independent experiments were performed in triplicates. This is a representative assay