Figure 3. Mutational Comparison of PLC.
Each gene box includes five percentages representing the mutational frequencies of activation and inactivation in cHCC-ICC, HCC, and ICC. Data layout is detailed in the legend. Only mutations are included. Genes are grouped by signaling pathways. Interaction between genes are indicated. Seven hallmarks of cancer are listed in the central box to indicate the potential influence of alterations among genes and signaling pathways (Hanahan and Weinberg, 2011).
See also Table S3.