图 4.

过表达ANXA2可促进肺腺癌细胞侵袭能力和肺腺癌中CCL18诱导的F-actin聚合。A：Western blot检测SiANXA2#2和SiANXA2#2+ANXA2转染效率；B：在加入或不加入10 ng/mL CCL18刺激的情况下，分析SiANXA2#2/A549和SiANXA2#2+ANXA2/A549细胞的侵袭能力，P < 0.05。以×400放大倍数捕获图像，比例尺：20 μm；C：在不同时长的10 ng/mL CCL18的刺激下SiANXA2#2/A549以及和SiANXA2#2+ANXA2/A549细胞中相对F-肌动蛋白含量。

Overexpression of ANXA2 promotes invasion of lung adenocarcinoma cells and CCL18-induced F-actin aggregation in lung adenocarcinoma cells. A: The transfection efficiency of SiANXA2#2 and SiANXA2#2+ANXA2 was detected by Western blot; B: Analyze the invasion ability of SiANXA2#2/A549 and SiANXA2#2+ANXA2/A549 cells with or without rCCL18 stimulation of 10 ng/mL. P < 0.05. Capture images at ×400 magnification. Scale bar: 20 μm; C: Relative F-actin content in SiANXA2#2/A549 and SiANXA2#2+ANXA2/A549 cells stimulated by 10 ng/mL CCL18 at different times.