Fig. 4.
Variant-containing isomiRs. (A) A subset of isoMiRmap’s output from the analysis of sample NA19257 (YRI population from the 1000 Genomes Project). Only SNP-containing isomiRs from hairpin hsa-mir-92a-1 with support by ≥10 reads are shown. Normalized read counts, hairpin coordinates, the molecules’ license plate and the unique identifier for the reference miRNA sequence were excluded for clarity. (B) Expression values across all samples from the YRI population (n = 95). IsoMiRmap correctly identifies all three (G|A, A|A, G|G) genotypes across the samples