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. Author manuscript; available in PMC: 2021 Jul 28.
Published in final edited form as: J Med Chem. 2020 Aug 11;63(17):9540–9562. doi: 10.1021/acs.jmedchem.0c00734

Figure 4.

Figure 4.

Time-kill assay for analogs 22 and 26 along with AZM and linezolid compared to DMSO-treated controls over 24 hours at 37 °C. Limit of detection is 100 CFU/mL. The data were analyzed via two-way ANOVA with post-hoc Dunnett’s test for multiple comparisons. Asterisks (*) denote statistically significant different (p < 0.05) between treatments with either 22, 26, AZM or linezolid in comparison to DMSO-treated cells.