Table 1.
Minimum inhibitory concentrations (MICs) for AZM-based analogs against E. faecium HM-965
![]() | |||||
|---|---|---|---|---|---|
| Compound | R | MICa | Compound | R | MICa |
| AZM | ![]() |
2 | 17 | ![]() |
0.25 |
| 3 | ![]() |
1 | 18 | ![]() |
0.25 |
| 4 | ![]() |
1 | 19 | ![]() |
0.06 |
| 5 | ![]() |
0.25 | 20 | ![]() |
0.06 |
| 6 | ![]() |
0.5 | 21 | ![]() |
0.06 |
| 7 | ![]() |
0.125 | 22 | ![]() |
0.007 |
| 8 | ![]() |
0.015 | 23 | ![]() |
0.06 |
| 9 | ![]() |
0.015 | 24 | ![]() |
1 |
| 10 | ![]() |
2 | 25 | ![]() |
1 |
| 11 | ![]() |
0.5 | 26 | ![]() |
1 |
| 12 | ![]() |
0.25 | 27 | ![]() |
8 |
| 13 | ![]() |
0.25 | 28 | ![]() |
2 |
| 14 | ![]() |
0.25 | 29 | ![]() |
> 64 |
| 15 | ![]() |
0.25 | 30 | ![]() |
> 64 |
| 16 | ![]() |
2 | 31 | ![]() |
> 64 |
AZM = acetazolamide.
MIC values in μg/mL against E. faecium strain HM-965






























