Table 2. Modeling Strategies Evaluated in the Studya.
| strategy | aggregated models | proper training set | calibration set | exchangeable |
|---|---|---|---|---|
| CCPnew | 10 |
Anew
|
Anew
|
× |
| CCPold | 10 |
Aold
|
Aold
|
|
| CCPpool | 10 |
(Aold ∪Anew) |
(Aold ∪Anew) |
|
| ICPoldnew | 1 | ∀Aold | ∀Anew | × |
| CCPAT | 10 |
Anew ∪
∀Aold
|
Anew
|
× |
| CCPAT2 | 10 |
Aold
|
Aold ∪
∀Anew
|
The
A and
A notation should be interpreted
as 1 or 9 parts of a 10-fold split of the data set A, where the folds are shifted for each ICP model in a similar fashion
as in cross-validation test-train splits. The last column indicates
whether the model’s calibration set is exchangeable with the
test data, i.e., theoretically guarantees valid models.









