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. 2021 Jul 14;9:676928. doi: 10.3389/fchem.2021.676928

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Copyright © 2021 Dong, Feng, Chen, Chen, Yang, Zhang, Li, Li, Ji, Yang, Hao, Chen and Wo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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In vivo distribution and migration of PbS QDs labeled ADSCs in a rat model of sciatic nerve injury. (A) Schematic illustration of the in vivo NIR-II imaging strategy. (B) Bright field photograph of the region of interest and NIR-II imaging of the experimental group (injected with PbS QDs labeled ADSCs) in a time course (0 d, 1 h, 1 d, 5 d, 7 d, 10 d, and 14 d post-injection). (C) Bright field photograph of the region of interest and NIR-II imaging of the control group (injected with pure PbS QDs) in a time course (0 d, 1 h, 1 d, 5 d, 7 d, 10 d, and 14 d post-injection). (D) Fluorescence area and (E) PL intensity of the proximal and distal sections of the sciatic nerve. (F) The ratio of PL intensity in distal/proximal nerve sections in the experimental group and the control group.