Figure 3.

Hard selective sweep in EPAS1 in kiangs

A: Composite-likelihood ratio (CLR) detected by SweeD and nucleotide diversity levels around EPAS1 gene in different populations, including kiang, Tibetan donkey, and plain donkey. Results indicate that this gene likely experienced a hard selective sweep in kiangs. B: Haplotype of nucleotide mutations in EPAS1 showing high level of divergence between kiangs and domestic donkeys. Pink, yellow, blue, and black indicate genotypes of Homozygous variant, Heterozygote, Homozygous reference, and No call, respectively. C: Partial EPAS1 amino acid sequences among different species.