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. Author manuscript; available in PMC: 2022 May 1.
Published in final edited form as: Prog Retin Eye Res. 2020 Sep 4;82:100901. doi: 10.1016/j.preteyeres.2020.100901

Figure 9.

Figure 9.

Size-dependent prolonged retention of microparticles and nanoparticles at the site of administration following subconjunctival injection in rats. Following administration of a 400-μg dose of 2 μm, 200 nm and 20 nm particles, the percentage dose remaining at the site of administration was determined up to 60 days post administration. The data is expressed as mean ± SD, n=4. †P < 0.05, compared with 20 nm nanoparticles; * P < 0.05, compared with the particle fraction remaining at time 0. Reprinted with permission from Amrite and Kompella, 2005. Copyright 2005 Wiley.