Table 2.

FDA approved topical eye drops for the treatment of glaucoma. The information was obtained from product information and related websites^*.

Classification	Recommended Dose (1 Drop, gtt)	Brand Name	Manufacturer
Alpha-2 adrenergic agonists e.g. apraclondine (for short-term use) and brimonidine tartrate	t.i.d. t.i.d. b.i.d. t.i.d.	Iopidine Alphagan, Alphagan-P Qoliana	Alcon Allergan Allergan Alcon
Alpha- and beta- adrenergic agonists (sympathomimetic agents); e.g., epinephrine, dipivalyl epinephrine	b.i.d. (q.d. or b.i.d.varies between patients) b.i.d.	Eppy/N, Glaucon, Epifrin, Epinal Propine	----- Canadian brands Allergan
Beta-blockers; e.g., bextaxolol is a beta-1 blocker while carteolol, levobunolol, metipranolol, and timolol are mixed beta-1 and beta-2 blockers	1 or 2 drops b.i.d. q.d. or b.i.d. 1 or 2 drops q.d. b.i.d. 1 or 2 drops b.i.d. q.d. or b.i.d. b.i.d. b.i.d. q.d. or b.i.d. q.d. or b.i.d. 1 or 2 drops q.d.	Betoptic, Betoptic S Betimol Betagan Carteolol HCl Kerlone Istalol Ocupress OptiPranolol Timoptic Timoptic XE Vistagan	Alcon Vistakon Pharm. Allergan Sandoz Inc. Merck ISTA pharm. Cadila Pharm. Bausch & Lomb Bausch & Lomb Merck Allergan
Carbonic anhydrase inhibitors**; e.g., acetazolamide, brinzolamide, and dorzolamide	t.i.d. t.i.d.	Azopt Trusopt	Alcon Merck
Cholinergic/parasympatho mimetic agents	Up to q.i.d. Up to q.i.d. Up to q.i.d. q.d. or b.i.d. 1 or 2 drops t.i.d. 1 or 2 drops b.i.d. or 1 or 2 drops b.i.w.	Pilocarpine Isopto Carpine Isopto Atropine Phospholine Iodide Carbachol Echothiophate Demecarium (dc)	Alcon/Sandoz Inc. Alcon Alcon Wyeth Pharm Alcon Wyeth Pharm. Merck
Prostaglandin analogs; e.g., bimatoprost, latanoprost, tafluprost, and travoprost	q.d. q.d. b.i.d. q.d. q.d. q.d.	Travatan Z Lumigan Rescula (dc) Xalatan Vyzulta Zioptan	Novartis Allergan Novartis Pfizer Bausch & Lomb Merck (Akorn Pharm.)
Rho kinase inhibitor; e.g., netarsudil	q.d.	Rhopressa	Aerie Pharm.
Prostaglandin and nitric oxide producer; e.g., latanoprstene bunod	q.d.	Vyzulta	Bausch + Lomb
Combination glaucoma drugs; e.g., brimonidine and timolol, dorzolamide and timolol, brinzolamide and brimonidine, netarsudil and latanoprost	b.i.d. b.i.d. t.i.d. q.d.	Combigan Cosopt Simbrinza Rocklatan	Allergan Akorn/Merck Alcon Aerie Pharm.

^*Recommended dosage information obtained from; www.accessdata.fda.gov, www.webmd.com/eye-health/which-medicines-treat-glaucoma#1, http://www.drugs.com/dosage/, http://www.goodrx.com, http://www.news-medical.net, and http://www.rxlist.com/. Abbreviations; b.i.d - twice a day, b.i.w - twice a week, dc - discontinued, q.d.- once a day, q.i.d -four times a day, and t.i.d.- three times a day.

^**Acetazolamide (Diamox) and methazolamide (Neptazane) are two orally dosed carbonic anhydrase inhibitors for reducing intraocular pressure.