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. Author manuscript; available in PMC: 2021 Jul 28.
Published in final edited form as: Clin Colorectal Cancer. 2019 Jul 2;18(3):192–199.e1. doi: 10.1016/j.clcc.2019.06.006

Fig 4.

Fig 4.

Female nude mice were inoculated subcutaneously with SW48 cells in the right flank and underwent treatment beginning 10 days post inoculation (plotted as day 10). Each data point represents average tumor volume for n=22 animals treated with LMB-100, Actinomycin D, combination of Actinomycin D and LMB-100, or PBS control. There is a significant difference between groups treated with RIT monotherapy and combination RIT-Actinomycin D therapy (p<0.05) beginning on day 15 (indicated by *). Actinomycin D combination therapy is significantly more effective than RIT monotherapy (p<0.05) beginning on day 17 (indicated by #).