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. 2021 Jul 14;11:720125. doi: 10.3389/fonc.2021.720125

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Copyright © 2021 Liao, Wang and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Genetic mutation landscape and drug sensitivity analysis of immune checkpoints in KIRC. (A) Oncoplot displaying genetic mutation landscape of immune checkpoints in TCGA KIRC cohort. (B) The activation and inhibition of immune checkpoints in KIRC-related pathways. (C) The correlation between immune checkpoints and drug or small molecules. The positive correlation means that the gene high expression is resistant to the drug, vise verse. (D) A heat map of the correlation between each member of immune checkpoints.