FIGURE 8.
The ER Ca2+ store and IP3/Ca2+ signaling in 5-HT-induced intestinal ion transports. (A,B) 5-HT-evoked duodenal I sc after TPEN (1 mM, n = 6) added to serosal (s) side. (C,D) 5-HT-evoked I sc after LiCl (30 mM, n = 6) was added to the serosal (s) side. (E) 5-HT-evoked I sc after dantrolene (Dan, 100 μM, n = 6) was added to the serosal side. Ctrl represents the control without drug treatment. Results are presented as mean ± SE. NS, no significant differences, *p < 0.05, **p < 0.01 vs. corresponding control by Student’s unpaired, two-tailed t-test.
