Figure 1.

Schematic representation of the measurement of (A) muscular layers, (B) submucosa, total wall, depth and width of the crypts, and (C) height and width of the villi. Were performed 64 measurements of each parameter for each animal. To obtain the width of the villi, the base, middle, and apex were measured and then the average of these values resulted in the final value (HE staining, 20× magnification, scale bar = 100 µm, Olympus CX31).