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. 2021 Jul 14;11:687499. doi: 10.3389/fcimb.2021.687499

Figure 9.

Figure 9

Area occupied by type I, type III, and total fibrillar collagen fibers (μm2). Data represented in box plots (median with 25 to 75 percentile), whiskers (2.5 to 97.5 percentile), and mean (+) (n = 6). *p < 0.05; **p < 0.01; ***p < 0.001. Photomicrograph of the area occupied by type I collagen fibers (yellow arrow) in control group and 2314 at 90-days post infection; by type III collagen fibers (green arrow) in group 2314 at 90- and 120-days post infection; and of total fibrillar collagen (black arrow) in group 2903 at 90- and 120-days post infection (Picrosirius Red staining, 20× magnification, scale bar = 25 µm, Olympus BX50). CG, control group. 2903: group infected with MHOM/BR/1975/M2903. 2314: group infected with MHOM/BR/2003/2314. 1655: group infected with MHOM/BR/2000/1655.