Table 3.

Data collection schedule

				Follow-up
	Inclusion	Preop SRS	Surgery	M3	M6	M9	M12
Consent	✓
Medical and surgical history	✓
History of the disease	✓
DS GPA classification	✓
Serum Pregnancy Test (for woman of childbearing age)	✓
Clinical examination	✓	✓		✓	✓	✓	✓
Previous and concomitant treatment	✓	✓		✓	✓	✓	✓
Toxicity Evaluation (NCI CTCAE v5.0)		✓	✓	✓	✓	✓	✓
MMSE and EORTC QLQ-C30 questionnaires	✓			✓	✓	✓	✓
Surgery information (date, quality of surgery and post-operative follow-up)			✓
Dosimetric brain MRI	✓
Dosimetric CT scan	✓
Tumor sample (FFPE block)	✓
Dose delivered to target volumes and organs at risk		✓
Paddick conformity Index and Gradient Index		✓
Brain MRI			✓a	✓	✓	✓	✓

^a within 48 h postoperatively (scanner accepted if MRI is not available)