Table 2.

GO and pathway enrichment analysis of target genes of miR-214-3p

Term ID	Term description	Gene count	Strength	FDR
Biological processes
GO:0009987	Cellular process	1186	0.03	1.1E−04
GO:0065007	Biological regulation	979	0.04	1.1E−04
GO:0050789	Regulation of biological process	942	0.05	2.92E−05
GO:0050794	Regulation of cellular process	896	0.05	2.88E−05
GO:0008152	Metabolic process	818	0.05	1.1E−04
Cell component
GO:0005623	Cell	1312	0.03	1.39E−07
GO:0005622	Intracellular	1225	0.06	7.97E−16
GO:0043226	Organelle	1062	0.05	5.67E−09
GO:0043229	Intracellular organelle	1042	0.05	1.28E−08
GO:0005737	Cytoplasm	993	0.07	1.68E−11
Molecular function
GO:0005488	Binding	1006	0.05	3.75E−06
GO:0005515	Protein binding	614	0.09	1.33E−06
GO:0043167	Ion binding	541	0.07	1.1E−03
GO:0003824	Catalytic activity	499	0.07	2.6E−03
GO:0097159	Organic cyclic compound binding	464	0.06	3.41E−02
KEGG pathways
hsa04310	Wnt signaling pathway	32	0.47	1.1E−04
hsa04390	Hippo signaling pathway	30	0.42	7.5E−04
hsa04550	Signaling pathways regulating pluripotency of stem cells	28	0.43	7.5E−04
hsa04261	Adrenergic signaling in cardiomyocytes	27	0.41	3.7E−03
hsa05200	Pathways in cancer	67	0.24	3.7E−03
Reactome pathways
HSA-3238698	WNT ligand biogenesis and trafficking	11	0.75	2.23E−02
HSA-198725	Nuclear events (kinase and transcription factor activation)	9	0.68	4.12E−02
HSA-450282	MAPK targets/ nuclear events mediated by MAP kinases	10	0.63	4.12E−02
HSA-8986944	Transcriptional regulation by MECP2	16	0.56	2.23E−02
HSA-187037	Signaling by NTRK1 (TRKA)	18	0.5	2.23E−02

GO gene ontology, KEGG Kyoto Encyclopedia of Genes and Genomes, FDR false discovery rate