Table 2.
Comparison of development set and the temporal validation set
| Characteristics | Development set (n = 546) | Temporal validation set (n = 195) | P values |
|---|---|---|---|
| Diagnosis of post-LT AKI | 301 (55.13%) | 98 (50.26%) | 0.867 |
| Demographics | |||
| Gender (male, n) | 472 (86.45%) | 171 (87.69%) | 1 |
| Age (y) | 50.61 (10.76) | 47.02 (10.07) | < 0.001 |
| Height (cm) | 167.77 (9.55) | 168.55 (6.42) | 0.292 |
| Weight (kg) | 64.25 (11.42) | 65.13 (11.14) | 0.35 |
| BMI | 22.71 (3.33) | 23.09 (3.06) | 0.164 |
| Predicting variables | |||
| IBIL (μmol/L) | 90.34 (97.04) | 96.91 (109.27) | 0.433 |
| UO (ml/(kg*h)) | 3.09 (2.2) | 3.03 (1.99) | 0.73 |
| Time under GA(min) | 543.0 (121.0) | 498.86 (111.18) | < 0.001 |
| PLT(109/L) | 94.45 (80.83) | 93.89 (76.62) | 0.932 |
| Steatosis grade ≥ 1 | 147 (26.92%) | 85 (43.59%) | 0.001 |
| Preoperative LOS (d) | 18.23 (21.82) | 15.78 (21.13) | 0.175 |
| EBL (ml) | 2066.38 (1906.18) | 1559.1 (1918.04) | 0.002 |
| ALB (g/L) | 35.56 (4.89) | 34.74 (6.96) | 0.133 |
| Bicarbonate (ml) | 124.04 (211.47) | 169.92 (203.77) | 0.009 |
| Colloid (ml) | 111.24 (301.53) | 32.31 (117.68) | < 0.001 |
| Pre-operative HE (n) | 129 (23.63%) | 37 (18.97%) | 0.899 |
| Cryoprecipitate(U) | 30.46 (16.03) | 26.53 (15.13) | 0.003 |
| ALT (U/L) | 131.08 (433.19) | 72.26 (211.4) | 0.069 |
| Pre-operative HM (n) | 209 (38.28%) | 91 (46.67%) | 0.249 |
AKI, acute kidney injury’; IBIL, indirect bilirubin; UO, urine output; GA, general anesthesia; PLT, platelets; LOS, length of stay; EBL, estimated blood loss; ALB, albumin; HE, hepatic encephalopathy; ALT, alanine transaminase; HM, hepatic malignancy