Table 1.

Demographic and clinical profiles of control and PD patients

Clinical parameters	Healthy controls	Stage II	Stage III	Stage IV	P value
Number of subjects	31	8	42	22	N/A
Age (years, mean ± SD)	63.94 ± 7.45	59.75 ± 7.55	61.62 ± 7.6	64.73 ± 8.14	0.2383
Age of onset (years, mean ± SD)	N/A	55 ± 7.53	53.6 ± 8.27	55.05 ± 10.89	0.6725
Sex (M/F)	17/14	5/3	26/16	12/10	0.0381
MMSE	N/A	26.63 ± 2.45	25.36 ± 2.32	24.18 ± 2.55	0.0392
UPDRS III	N/A	19.75 ± 2.90	25.1 ± 2.78	29.59 ± 4.45	< 0.0001

M male, F female, MMSE Mini-Mental State Examination, UPDRS III Unified Parkinson’s Disease Rating Scale part III, N/A not applicable