Figure 2:

Mechanoresponse of PHH cells revealed by viscoelastic gel. (A) schematic of PHH cell response. (lower panel) Cell spreading on elastic and viscoelastic gels (B) Bright-field image of primary human hepatocytes plated on elastic, viscoelastic and glass substrates at 24hrs and 48 hrs. Scale bar, 50 μm. Hepatocyte cell areas on elastic, viscoelastic, and on glass substrates after 24 and 48 hrs. Error bars represent standard error of the mean (for 24 hrs N=100, 29 and 104 and for 48hrs N=103, 46 and 102 cells on Elastic, viscoelastic and on glass substrates respectively). p-values are determined from Student’s t-test for unpaired samples ( n.s p > 0.05, * p<0.05; ** p<0.01, *** p<0.001 ).