Table 1.
Demographic characteristics of secondary syphilis patients and healthy controls.
| Microarray study | Validation study | |
|---|---|---|
| Secondary syphilis group | ||
| Number of participants | 6 | 21 |
| Sex (male/female) | 2/4 | 10/11 |
| Age (years, average; range) | 36 (18-52) | 34 (27-42) |
| Duration of disease (days, average; range) | 28 (14-50) | 26 (10-50) |
| TPHA (positive/negative) | 6/0 | 21/0 |
| TRUST titer (positive/negative) | 6/0 | 21/0 |
| TRUST titer 1 : 128 | 2 | 7 |
| TRUST titer 1 : 64 | 1 | 3 |
| TRUST titer 1 : 32 | 2 | 3 |
| TRUST titer 1 : 16 | 1 | 6 |
| TRUST titer 1 : 8 | 0 | 2 |
| Skin lesions and symptoms | ||
| Roseola | 1 | 6 |
| Plaques on palms and/or soles | 2 | 7 |
| Moth-eaten alopecia | 1 | 5 |
| Condylomata lata | 1 | 3 |
| Mild flu-like symptoms (i.e., headache, myalgias) | 2 | 8 |
| Adenopathy | 2 | 10 |
| Healthy control group | ||
| Number of participants | 6 | 14 |
| Sex (male/female) | 2/4 | 6/8 |
| Age (years, average; range) | 34 (27-42) | 35 (23-47) |
| TPHA (positive/negative) | 0/6 | 0/14 |
| TRUST titer (positive/negative) | 0/6 | 0/14 |
| Skin lesions and symptoms | 0 | 0 |
TPHA: Treponema pallidum particle hemagglutination assay; TRUST: toluidine red unheated serum test.