Table 7.

Worldwide clinical trials related to COVID-19 treatments.

	PubChem (CID)	Category and drug	APOD Score (Benefits-Risks)	N-APOD (WRGLSBADMET)	Country
		Strong safety profile
1	10445549	Galidesivir	8–1	57909079560	US
2	3113817	Riamilovir	8–1	46209079370	US
3	37542	Ribavirin	8–1	47809079470	CN, US
4	464205	Tenofovir	8–1	58609079460	CN, US
5	24769759	Azvudine	7–1	57608068460	CN
6	60877	Emtricitabine	7–1	45407078371	CN, US
7	145996610	Molnupiravir	7–1	67809069560	US
8	492405	Avigan	7–2	34405077272	JP
9	16132300	Aviptadil	7–2	99909059640	EU, US
10	44205240	Baricitinib	7–2	77208068450	CA, EU, US
11	2973	Deferoxamine	7–2	99909059640	US
		Moderate safety profile
12	5426	Thalidomide	6–2	54205067262	US
13	2536	Camostat	6–3	76429057441	JP, US
14	122527270	AT-527	5–3	99839047731	EU
15	864	Alpha lipoic acid	5–3	44235055353	CN
16	139595263	Anakinra	5–3	99629047631	AU, EU, US
17	65028	Oseltamivir	5–3	65426056452	US
18	121304016	Remdesivira	5–3	99839047731	AU, EU, US, WHO
19	5361	Suramin	5–3	99939047731	CN
20	11561674	Apremilast	5–4	97238046532	EU, US
21	6167	Colchicine	5–4	76225046443	US
22	5743	Dexamethasone	5–4	76636046543	UK, US
23	6741	Methylprednisolone	5–4	75636046543	US
		Weak safety profile
24	213039	Darunavir	4–4	99659035722	US
25	26879	Levamisole	4–4	42032044255	US
26	4594	Omeprazole	4–4	66246045443	US
27	40632	Pirfenidone	4–4	31031054165	CN
28	25126798	Ruxolitinib	4–4	64245045444	CA, CN, US
29	9926791	Tofacitinib	4–4	65235045443	US
30	11285588	Danoprevir	4–5	99669035713	CN, EU
31	9875401	Rivaroxaban	4–5	86257035523	US
32	107770	Dihydroartemisinine	3–5	55253033445	CN
33	3495	Glycyrrhizinate	3–5	99979024813	CN
34	3899	Leflunomide	3–5	56253033445	CN
35	156391	Naproxen	3–5	43263033346	US
36	71481097	Selinexor	3–5	89466024624	US
37	52947239	Triazavirin	3–5	59499033624	CN
38	71226662	Acalabrutinib	3–6	96467024614	EU
39	124081896	Baloxavir Marboxil	3–6	99078024614	CN
40	9820008	Vidofludimus	3–6	75465033525	US
41	447043	Azithromycin	2–6	99989023804	AU, UK, US
42	60606	Clopidogrel	2–6	64073022426	CA, US
43	25151504	Cobicistat	2–6	99699013804	US
44	107970	Fingolimod	2–6	63684022526	US
45	3652	Hydroxychloroquine	2–6	64473022526	AU, UK, US, WHO
46	5291	Imatinib	2–6	97475013615	US
47	3961	Losartan	2–6	85486022615	US
48	6918456	Prasugrel	2–6	76074022526	CA
49	154731616	RBT-9	2–6	98476023715	EU
50	392622	Ritonavir	2–6	99899013804	AU, CN, UK, US, WHO
51	60846	Valsartan	2–6	86487023615	US
52	3689	Ifenprodil	2–7	63472022527	US
53	72734520	Abivertinib	1–7	98686012705	US
54	131411	Arbidol	1–7	95285012606	CN, US
55	60823	Atorvastatin	1–7	96897012805	US
56	74989	Atovaquone	1–7	73293011517	US
57	46215462	Bemcentinib	1–7	97496012706	US
58	6918155	Ciclesonide	1–7	97296012606	US
59	11502129	Glucocorticoid	1–7	77694011717	CN
60	92727	Lopinavir	1–7	95898012705	AU, CN, UK, US, WHO
61	135423438	Nintedanib	1–7	97486012705	US
62	54454	Simvastatin	1–8	85294011607	CA
63	2719	Chloroquine	0–8	63291010518	AU, CN, EU, US, WHO
64	5280795	Cholecalciferol	0–8	71291010418	CA
65	3191	Ebastine	0–8	93091000508	CN
66	122262	Piperaquine	0–8	96092000608	CN
67	73078	Tetrandrine	0–8	98094001607	US
68	9916461	Tradipitant	0–8	99094001607	US

Drugs are oral formulations unless indicated.

^aInjection.