TABLE 1.

Susceptibility of the Mmas porin mutants to antibiotics.

Strains	AMI	APR	AZI	CIP	CLA	ERY	TET	KAN	CEF	IMI	TIG	LIN
Mmas CIP108297	16–32	2	1–2	32–64	0.25	8–16	32	8	64	32	2–4	16
MmasΔmmpA	32	2–4	1–2	128	0.5	8	8	8	64	64–128	4	16
MmasΔmmpB	16–64	4	2	32–64	0.5	16	16	8	64	32	4	16
MmasΔmmpA/pOMK-mmpA	64	2	2	32	1	32	8	nd	64	64	4	16
MmasΔmmpA/pOMK-mmpAB	32	4	4	32	1	16	16	nd	64	64	4	16
MmasΔmmpB/pOMK-mmpB	32	4	2	32	0.25	8	8	nd	64	32	2–4	16
MmasΔmmpB/pOMK-mmpAB	32	4	2	32	0.5	8	8	nd	64	32	4	16

MIC were determined in Mueller-Hinton II broth and MIC values are in μg/ml.AMI, amikacin; APR, apramycin; AZI, azithromycin; CEF, cefoxitin; CIP, ciprofloxacin; CLA, clarithromycin; ERY, erythromycin; IMI, imipenem; KAN, kanamycin; LIN, linezolid; TET, tetracycline; TIG, tigecycline. MIC determinations were performed two to three times on independent culture batches. nd, not determined.