FIGURE 4.

Inactivation of the MST markers, Cryptosporidium, and Giardia after model optimization (solid lines) and as reported in experimental studies (dots, Supplementary Table 4), plotted as time to first log₁₀ reduction (TFL, days) values log₁₀-transformed (log₁₀ (TFL) in function of the temperature. Ordinary-least-square regressions (dashed lines) were fitted to the literature values, shown with their 95% prediction intervals (shaded). The intercept and the slope of the solid lines were the result of the model optimization. These values were used as model input parameters a₀ and a₁ in Equation 2 (Table 1).