Figure 4. Effect of NH2-terminal acetylation on pH sensitivity (Bohr effect) of alligator and human Hbs in the presence and absence of anions.

(A and B) Effect of Cl− on O2-affinities of alligator and human Hbs as a function of pH. (C) Effect of ATP on the O2-affinity of alligator Hb as a function of pH. (D) Effect of DPG on the O2-affinity of human Hb as a function of pH.