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. 2021 Jul 14;12:712614. doi: 10.3389/fimmu.2021.712614

Figure 2.

Figure 2

Effects of GOS/inulin supplementation during pregnancy on the fecal microbiota composition and SCFA levels. (A) Analysis of β-diversity by unweighted UniFrac-based PCoA of stools from dams fed a control or prebiotic diet before gestation (GD0) and at 7, 14 and 18 gestational days (GD7, GD14 and GD18, respectively). (B) α-Diversity of stools from dams fed a control (white) or prebiotic diet (gray) on GD0, GD7, GD14 and GD18. (C) Table summarizing the relative abundance of phyla and families in the fecal microbiota. “+” indicates an increase and “-” indicates a decrease in the prebiotic group compared to the control group (*=p<0.05, ** = p<0.01, *** = p<0.001). (D) Graphical representation and heatmap of sex variance in stools from dams fed a control or prebiotic diet at GD18. (E) Evaluation of SCFA (acetate, propionate, and butyrate) levels in stools from dams fed a control (white) or prebiotic diet (gray) on GD0, GD7, GD14 and GD18 (** = p<0.01, *** = p<0.001).