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. 2021 Jul 3;12(17):5345–5354. doi: 10.7150/jca.60543

Table 1.

The top 10 upregulated and downregulated mRNAs from the RNA-seq

Gene name Fold changes P-value
Endothelial Cell-specific Molecular 1 ESM1 12.31 0.0089
Forkhead Box Q1 FOXQ1 11.72 0.0171
Tropomyosin 4 TPM4 9.59 0.0137
Tescalcin Tescalcin 9.21 0.0392
PR Domain Zinc Finger Protein 13 PRD13 6.65 0.0023
Matrix Metallopeptidase 28 MMP28 6.52 0.0243
Adenylate Cyclase 9 ADCY9 5.54 0.0217
Purinergic Receptor P2Y13 P2RY13 5.47 0.0291
ER Membrane Protein Complex Subunit 1 EMC1 5.11 0.0337
Frizzled Class Reptor 3 FZD3 5.03 0.0415
Transmembrane and immunoglobulin domain-containing protein 1 TMIGD1 -12.35 0.0423
Guanylate cyclase activator 2B GUCA2B -11.48 0.0216
Four and a Half LIM Domains 1 FHL1 -11.34 0.0062
Carbonic anhydrase 1 CA1 -8.43 0.0415
Bone morphogenetic protein 3 BMP3 -6.94 0.0243
Ras-related and estrogen-regulated growth inhibitor-like protein RERGL -6.78 0.0221
XK-related protein 4 XKR4 -5.91 0.0131
Proline-rich membrane anchor 1 PRIMA1 -5.67 0.0079
Kv channel-interacting protein 4 KCNIP4 -5.41 0.0235
Peptidase inhibitor 16 PI16 -5.31 0.0212