Figure 3.

Analyses of cyclin D1 interaction with the C33A genome. (A) Cyclin D1 occupies region of abundantly genes from the distribution of potential peak in genome. (B) The length of peaks mostly are between 500 and 2000, while focused on nearly 1000 bp. (C and D) Most of the binding sites were located in intergenic or intron. (E and F) The function of the downstream genes, for example, cellular component, molecular function, biological process; based on the functional annotation analysis, there were a large number of gene sets associated with signal transduction. (G) The TF motifs enriched within the interval regions associated with cyclin D1, which suggested that cyclin D1 bound promoter regions with a high content of CpG dinucleotide.