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. 2021 Jun 22;12(17):5125–5135. doi: 10.7150/jca.53282

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BZW2 promotes the proliferation of HCC cells. (A) The relative proliferation rate of transfected cells was determined by CCK-8 assay at the indicated times. (B) Photos of colony formation (left) and bar graph (right). (C, D) Effect of BZW2 depletion or overexpression on cell cycle distribution and cell apoptosis, respectively. (E) Photos (left) and bar plot (right) of migration in BZW2-overexpressing or BZW2-knockdown cells. (F) The invasion assay results after incubation in Transwell chambers for 48 h. The data are from three independent experiments and expressed as the mean ± SD. *P < 0.05, **P < 0.01.