Table 2.

Median biochemistry at baseline (efficacy population, n = 34).

	Low-dose group (n = 17)	High-dose group (n = 17)	Overall population (n = 34)
ACTH, pmol/L (min, max)	9.8 (1.0, 25.3)	14.0 (1.0, 28)	10.8 (1.0, 28.0)
24-h UFC, nmol/d (min, max)	357.4 (122.0, 2823.8)	251.6 (56.9, 2341.0)	357.0 (56.9, 2823.8)
LNSC, nmol/L (min, max)	7.2 (1.2, 36.5)	5.4 (2.1, 32.7)	6.6 (1.2, 36.5)
Serum cortisol, nmol/L (min, max)	483.0 (141.0, 748.0)	431.0 (235.0, 1352.0)	459.5 (141.0, 1352.0)

To convert values of ACTH to pg/mL, divide by 0.22; UFC to µg/24 h, divide by 2.76; LNSC and serum cortisol to µg/dL, divide by 27.6.

ACTH, adrenocorticotropic hormone; LNSC, late-night salivary cortisol; SD, standard deviation; UFC, urinary free cortisol.