Table 1.
Cohort Characteristics, All Bone Metastases
| Statistic* | ALL N=40,993 | FREE N=17,307 | OPD N=23,686 | P-value† | |
|---|---|---|---|---|---|
| Demographics | |||||
| Gender | |||||
| Female | N (%) | 17480 (43%) | 7190 (42%) | 10290 (43%) | <0.001 |
| Male | N (%) | 23513 (57%) | 10117 (58%) | 13396 (57%) | |
| Age group | |||||
| 65–74 | N (%) | 21193 (52%) | 8739 (50%) | 12454 (53%) | <0.001 |
| 75–84 | N (%) | 14963 (37%) | 6459 (37%) | 8504 (36%) | |
| 85+ | N (%) | 4837 (12%) | 2109 (12%) | 2728 (12%) | |
| Treatment Characteristics | |||||
| Major procedure(s) | |||||
| Yes | N (%) | 12010 (29%) | 4872 (28%) | 7138 (30%) | <0.001 |
| No | N (%) | 28,983 (71%) | 12,435 (72%) | 16,548 (70%) | |
| Chemotherapy | |||||
| Yes | N (%) | 30,492 (74%) | 13188 (76%) | 17304 (73%) | <0.001 |
| No | N (%) | 1,0501 (26%) | 4,119 (24%) | 6,382 (27%) | |
| Radiation modality | |||||
| SBRT | N (%) | 2840 (7%) | 818 (5%) | 2022 (9%) | <0.001 |
| EBRT | N (%) | 35697 (87%) | 14986 (87%) | 20711 (87%) | |
| IMRT | N (%) | 2456 (6%) | 1503 (9%) | 953 (4%) | |
| Course length | |||||
| 1–10 services | N (%) | 29,939 (73%) | 11118 (64%) | 18821 (79%) | <0.001 |
| 11+ services | N (%) | 11,054 (27%) | 6189 (36%) | 4865 (21%) | |
| Expenditures | |||||
| Provider fees (USD, $) | Median (IQR) | 1234 (948, 1655) | 1348 (1025, 1785) | 1158 (900, 1554) | <0.001 |
| Technology fees (USD, $) | Median (IQR) | 4429 (3245, 6094) | 4528 (3522, 6268) | 4332 (3104, 5942) | <0.001 |
| Clinical Outcomes | |||||
| Death during 90-day episode | |||||
| No death | N (%) | 32382 (79%) | 13705 (79%) | 18677 (79%) | 0.6 |
| Within 1–30 days | N (%) | 1993 (5%) | 846 (5%) | 1147 (5%) | |
| Within 31–60 days | N (%) | 3586 (9%) | 1477 (9%) | 2109 (9%) | |
| Within 61–90 days | N (%) | 3032 (7%) | 1279 (7%) | 1753 (7%) | |
Abbreviations: 95% CI, 95% confidence interval; EBRT, external beam radiotherapy; FREE, freestanding; IMRT, intensity modulated radiotherapy; OPD, hospital-affiliated outpatient; OR, odds ratio; SBRT, stereotactic body radiotherapy.
*
Statistics presented: N (%); Median (IQR)
†
Statistical tests performed: chi-square test of independence; Wilcoxon rank-sum test