Table 1.

Naphthyl amides

Entry	R1	Aβ40 (%) Inhibition a	Notch1 Processing b
2	i-Pr	58	No change
3	H	0	n.t.
4	CH3	15	n.t.
5	t-Bu	52	No change
6	cyclic-Pr	37	No change

n.t. = not tested

^a,bSee References and Notes sections for assay descriptions

^aCompounds were tested at 100 μM. Inhibitory effects on Aβ40 production were recorded as a percentage in comparison with DMSO control.

^bCompounds were tested at 100 μM. Effects on Notch processing were recorded (Western Blot) in comparison with DMSO control.