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. Author manuscript; available in PMC: 2021 Jul 28.
Published in final edited form as: Bioorg Med Chem Lett. 2016 Mar 12;26(9):2129–2132. doi: 10.1016/j.bmcl.2016.03.040

Table 4.

Benzofuranoyl amide analogs

graphic file with name nihms-1723048-t0019.jpg
Entry R7 R8 R9 R’° Αβ40 (%)
Inhibitiona 		Notch 1
Processing b
30 H H H H 40 No change
31 H H Cl Cl 51 No change
32 H Me Cl Cl 0 n.t.
33 OMe H Cl Cl 75 No change
34 OMe H Cl F 49 No change
35 OMe H F Cl 23 No change
36 OEt H Cl Cl 58 No change
a, b

See Table 1 notes, n.t. = not tested.