Fig. 9.

βIII-tubulin positive nerve fiber density and mast cells are positively correlated in PCB exposed bladders. Mice were exposed to PCBs via the maternal diet throughout gestation and lactation and bladders collected from male and female offspring at postnatal day (P) 28–31. Correlation between the percentage area of suburothelium βIII-tubulin positive versus total mast cells/bladder area for each sample. (A) Both sexes of 0.1 mg/kg and 6 mg/kg PCB groups were combined, n = 22 samples. (B) For each sex independently, 0.1 mg/kg and 6 mg/kg PCB groups were combined to determine a correlation, n = 10 male PCB samples; n = 12 female PCB samples. (C) Both sexes were combined from each group separately to determine a correlation, n = 10 control samples, n = 12 PCB 0.1 mg/kg/d, n = 10 PCB 6 mg/kg/d. * indicates significance determined by Pearson r at p ≤ 0.05.