Table 2.
Characteristics at presentation for patients with vitamin d−mediated hypercalcemia, stratified by disease group
Feature, n(%) | 24HD (n = 9) | Sarcoidosis (n = 15) | Lymphoma (n = 7) | EVT (n = 6) |
---|---|---|---|---|
Urinary stones | 5 (55%) | 4 (27%) | 0 (0%) | 0 (0%) |
Severe symptoms of hypercalcemiaa | 3 (33%) | 6 (40%) | 6 (86%) | 3 (50%) |
Palpitation | 1 (11%) | 0 (0%) | 0 (0%) | 1 (17%) |
Weight loss | 2 (22%) | 3 (20%) | 0 (0%) | 2 (33%) |
Pulmonary symptomsb | 0 (0%) | 3 (20%) | 2 (29%) | 0 (0%) |
Asymptomatic | 2 (22%) | 3 (20%) | 1 (14%) | 3 (50%) |
Abbreviations: 24HD, 24-hydroxylase deficiency; EVT, exogenous vitamin D toxicity.
a Symptoms included loss of appetite, nausea, vomiting, abdominal pain, constipation, polyuria, polydipsia, dehydration, constitutional symptoms (fatigue, weakness, muscle pain), altered mental status, or poor feeding or failure to thrive (in neonates).
b Symptoms included cough or shortness of breath.