FIGURE 5.

Tissue-level simulations in the two and four highest-level clusters of (A) SNLV and (B) ICMP models. In the center of each sub-plot we show the four highest-level clusters of the dendrogram produced by AHC. The two highest-level clusters are noted as 2/1 and 2/2 and the four highest clusters are noted as 4/1, 4/2, 4/3, and 4/4. Note that for ICMP clusters 2/2 and 4/4 are identical since no bifurcation of the dendrogram occurs at this level. Each plot surrounding the dendrogram shows the S1–S2 coupling intervals that resulted in sustained functional re-entry for different conductivity values and is labeled after the cluster that it has been created from (X-axis represents different tissue conductivity values in mS/m and Y-axis represents S1–S2 coupling intervals that resulted in sustained functional re-entry). For all clusters, ICMP models developed sustained functional re-entry over a wider range of S1–S2 coupling intervals for the entire range of conductivity values, compared to SNLV.