TABLE 3.

Action potential biomarkers for the base BOFC and derived SNLV and ICMP models.

Model	RMP (mV)	Vmax (mV)	Tmax (ms)	dV/dt (V/s)	APD30 (ms)	APD50 (ms)	APD90 (ms)	Tri(90-30) (ms)	Tri(30/90)	Tri(90-50) (ms)	Tri(50/90)
Base	−84.0	53.8	0.48	287.2	123.7	226.5	276.3	152.6	0.45	49.8	0.82
SNLV	−84.0	55.5	0.48	290.7	98.2	210.5	256.8	158.6	0.38	46.3	0.82
ICMP	−84.0	57.6	0.48	295.1	77.2	197.5	242.5	165.3	0.32	45.0	0.81

Biomarkers were obtained by pacing the action potential models at 500 ms.

APD30, APD50, and APD90, action potential duration at 30, 50, and 90% repolarization; dV/dt, upstroke velocity; RMP, resting membrane potential; Tmax, time to maximal voltage upstroke; Tri(90-30), triangulation index defined as APD90-APD30; Tri(30/90), triangulation index defined as APD30/APD90; Tri(90-50), triangulation index defined as APD90-APD50; Tri(50/90), triangulation index defined as APD50/APD90; Vmax, maximal voltage of action potential upstroke. Tri(30/90) and Tri(50/90) are unitless.