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Fig. 5. (A and B) PA images and quantified PA signals of OctaNPs in an aqueous pH 6 medium with increasing concentrations of GSH (0–40 μM). (C) PA and US B-scan images of normal tissue (right flank of mouse) and tumor before and after in situ injection with OctaNPs (200 μL, 0.1 mg mL−1) under 1200 nm pulse laser excitation. (D) Quantified PA signal in normal tissue and in a HepG2 mice model. Sample size: n = 3.