Table 2.
Oncological outcome at 6-yr follow-up
| Unadjusted analyses |
Adjustment A |
Adjustment B |
||||||
|---|---|---|---|---|---|---|---|---|
| RALP | RRP | RR (95% CI) | p value | RR (95% CI) | p value | RR (95% CI) | p value | |
| All patients | ||||||||
| Residual diseasea | 37/1504 (2) | 13/596 (2) | 1.13 (0.66; 1.93) | 0.7 | 0.97 (0.55; 1.72) | 0.9 | 0.69 (0.31; 1.55) | 0.4 |
| Missing | 41 | 37 | 129 | 192 | ||||
| BCRb | 218/1538 (14) | 98/631 (16) | 0.91 (0.72; 1.16) | 0.5 | 0.89 (0.65; 1.21) | 0.5 | 0.86 (0.57; 1.29) | 0.5 |
| Missing | 7 | 2 | 88 | 151 | ||||
| Not curedc | 334/1492 (22) | 131/611 (21) | 1.04 (0.76; 1.43) | 0.8 | 0.97 (0.71; 1.32) | 0.9 | 0.86 (0.56; 1.33) | 0.5 |
| Missing | 53 | 22 | 156 | 218 | ||||
| Experienced surgeons | ||||||||
| Residual diseasea | 51/2203 (2) | 19/681 (3) | 0.83 (0.51; 1.36) | 0.5 | 0.75 (0.45; 1.26) | 0.3 | 0.46 (0.23; 0.93) | 0.03 |
| Missing | 48 | 38 | 166 | 236 | ||||
| BCRb | 321/2244 (14) | 113/717 (16) | 0.91 (0.73; 1.12) | 0.4 | 0.93 (0.71; 1.23) | 0.6 | 0.77 (0.56; 1.06) | 0.1 |
| Missing | 7 | 2 | 121 | 191 | ||||
| Not curedc | 483/2174 (22) | 157/687 (23) | 0.99 (0.75; 1.3) | 0.9 | 0.96 (0.73; 1.25) | 0.8 | 0.82 (0.6; 1.11) | 0.2 |
| Missing | 77 | 22 | 210 | 279 | ||||
BCR = biochemical recurrence; CI = confidence interval; PSA = prostate-specific antigen; RALP = robot-assisted laparoscopic prostatectomy; RR = relative risk; RRP = retropubic radical prostatectomy.
Adjustment A: pathology T stage, pathology Gleason score, preoperative PSA level, pathology prostate weight.
Adjustment B: same as adjustment A plus surgeon annual volume and surgeon prior experience.
PSA > 0.25 ng/ml at 3 mo.
PSA < 0.25 ng/ml at 3 mo and PSA > 0.25 ng/ml at 1, 2, or 6 yr of follow-up.
PSA > 0.25 ng/ml at any time or radiotherapy, chemotherapy, or hormone therapy at 1, 2, or 6 yr of follow-up.