Table 2.
Significant index single nucleotide polymorphisms associated with low testosterone in each clump
| Chromosome | SNP (index SNPs in each LD region) | Base pair | Cytoband | Risk allele | Stage 1 |
Stage 2 |
Combine |
Independent? | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Frequency in low T | Frequency in non–low T | OR | p value | Frequency in low T | Frequency in non–low T | OR | p value | OR | p value | ||||||
| 1 | rs114165349 | 27021913 | 1p36.11 | C | 0.03 | 0.02 | 1.32 | 4.33E-11 | 0.03 | 0.02 | 1.47 | 4.87E-08 | 1.35 | 3.41E-17 | N |
| 1 | 1:27335529_GGAATGCAGT_G | 27335529 | 1p36.11 | G | 0.03 | 0.02 | 1.33 | 1.12E-11 | 0.03 | 0.02 | 1.56 | 4.15E-10 | 1.38 | 2.43E-19 | Y |
| 1 | rs28385651 | 27696330 | 1p36.11 | C | 0.04 | 0.04 | 1.17 | 5.63E-06 | 0.04 | 0.04 | 1.24 | 2.54E-04 | 1.18 | 8.40E-09 | N |
| 2 | rs1260326 | 27730940 | 2p23.3 | T | 0.42 | 0.39 | 1.14 | 7.71E-22 | 0.41 | 0.40 | 1.11 | 1.47E-05 | 1.13 | 9.93E-26 | Y |
| 2 | rs3817588 | 27731212 | 2p23.3 | T | 0.82 | 0.81 | 1.11 | 7.57E-09 | 0.82 | 0.81 | 1.08 | 1.66E-02 | 1.10 | 5.21E-10 | N |
| 2 | rs13013484 | 27988821 | 2p23.2 | A | 0.74 | 0.73 | 1.08 | 2.45E-07 | 0.74 | 0.73 | 1.08 | 2.86E-03 | 1.08 | 2.43E-09 | N |
| 2 | rs13030345 | 28003174 | 2p23.2 | T | 0.18 | 0.17 | 1.11 | 1.32E-09 | 0.18 | 0.17 | 1.07 | 2.29E-02 | 1.10 | 1.48E-10 | N |
| 2 | rs77775907 | 31609942 | 2p23.1 | G | 0.97 | 0.96 | 1.39 | 3.96E-15 | 0.97 | 0.97 | 1.29 | 2.94E-04 | 1.36 | 6.90E-18 | Y |
| 2 | rs113017476 | 31989359 | 2p23.1 | G | 0.97 | 0.96 | 1.38 | 2.09E-16 | 0.97 | 0.96 | 1.38 | 2.42E-06 | 1.38 | 2.71E-21 | N |
| 2 | rs148325193 | 32178523 | 2p22.3 | AT | 0.46 | 0.44 | 1.07 | 3.33E-07 | 0.45 | 0.44 | 1.08 | 1.03E-03 | 1.07 | 1.33E-09 | N |
| 2 | rs72796891 | 32447408 | 2p22.3 | A | 0.96 | 0.95 | 1.31 | 2.63E-15 | 0.96 | 0.95 | 1.30 | 9.83E-06 | 1.31 | 1.34E-19 | N |
| 2 | rs111471249 | 32834193 | 2p22.3 | C | 0.97 | 0.96 | 1.30 | 1.18E-11 | 0.97 | 0.96 | 1.29 | 1.47E-04 | 1.29 | 7.74E-15 | N |
| 3 | rs7626388 | 138089038 | 3q22.3 | G | 0.36 | 0.34 | 1.09 | 8.55E-10 | 0.36 | 0.34 | 1.05 | 4.20E-02 | 1.08 | 2.10E-10 | Y |
| 4 | rs9884390 | 69373407 | 4q13.2 | T | 0.78 | 0.77 | 1.08 | 7.86E-07 | 0.78 | 0.76 | 1.12 | 3.84E-05 | 1.09 | 2.22E-10 | Y |
| 4 | rs6811902 | 88213884 | 4q22.1 | C | 0.45 | 0.43 | 1.07 | 1.18E-06 | 0.45 | 0.43 | 1.07 | 2.60E-03 | 1.07 | 1.24E-08 | Y |
| 4 | rs114087689 | 104064037 | 4q24 | T | 0.02 | 0.01 | 1.28 | 1.19E-06 | 0.02 | 0.01 | 1.35 | 7.14E-04 | 1.30 | 3.59E-09 | N |
| 4 | rs17289915 | 104491078 | 4q24 | G | 0.02 | 0.01 | 1.52 | 3.02E-15 | 0.02 | 0.01 | 1.44 | 5.73E-05 | 1.50 | 8.98E-19 | Y |
| 4 | rs115260227 | 104774698 | 4q24 | G | 0.01 | 0.01 | 1.55 | 2.27E-14 | 0.02 | 0.01 | 1.63 | 6.54E-07 | 1.57 | 8.42E-20 | N |
| 6 | rs11156429 | 105364421 | 6q16.3 | T | 0.47 | 0.45 | 1.08 | 1.84E-09 | 0.47 | 0.45 | 1.08 | 1.30E-03 | 1.08 | 1.05E-11 | Y |
| 7 | rs10278686 | 15031450 | 7p21.2 | C | 0.53 | 0.51 | 1.11 | 1.28E-13 | 0.52 | 0.50 | 1.08 | 1.38E-03 | 1.10 | 1.08E-15 | Y |
| 7 | rs34785619 | 97946299 | 7q21.3 | C | 0.20 | 0.18 | 1.12 | 4.60E-11 | 0.20 | 0.18 | 1.09 | 3.28E-03 | 1.11 | 7.33E-13 | Y |
| 10 | rs11461906 | 64768139 | 10q21.3 | T | 0.91 | 0.89 | 1.13 | 2.13E-07 | 0.90 | 0.90 | 1.08 | 4.41E-02 | 1.11 | 4.15E-08 | N |
| 10 | rs10822120 | 64829314 | 10q21.3 | T | 0.63 | 0.60 | 1.13 | 8.63E-18 | 0.62 | 0.60 | 1.08 | 7.29E-04 | 1.12 | 7.73E-20 | N |
| 10 | rs7896280 | 64868355 | 10q21.3 | C | 0.76 | 0.74 | 1.08 | 3.17E-06 | 0.76 | 0.74 | 1.10 | 2.42E-04 | 1.08 | 4.46E-09 | N |
| 10 | rs7084569 | 64876554 | 10q21.3 | G | 0.57 | 0.52 | 1.20 | 1.28E-39 | 0.56 | 0.52 | 1.18 | 3.40E-12 | 1.19 | 3.84E-50 | Y |
| 10 | rs72829138 | 64907575 | 10q21.3 | C | 0.19 | 0.17 | 1.12 | 3.64E-10 | 0.18 | 0.17 | 1.09 | 6.21E-03 | 1.11 | 1.06E-11 | N |
| 10 | rs117452816 | 65043795 | 10q21.3 | T | 0.93 | 0.93 | 1.17 | 1.14E-08 | 0.93 | 0.92 | 1.14 | 5.63E-03 | 1.16 | 2.33E-10 | N |
| 10 | 10:65082562_CAAA_C | 65082562 | 10q21.3 | CAAA | 0.21 | 0.19 | 1.14 | 4.72E-15 | 0.21 | 0.19 | 1.18 | 6.83E-09 | 1.15 | 4.47E-22 | N |
| 10 | rs6479896 | 65126832 | 10q21.3 | T | 0.57 | 0.52 | 1.24 | 8.30E-55 | 0.57 | 0.52 | 1.21 | 2.65E-16 | 1.23 | 3.06E-69 | N |
| 10 | rs76865584 | 65205928 | 10q21.3 | G | 0.87 | 0.85 | 1.13 | 1.07E-09 | 0.87 | 0.85 | 1.15 | 7.12E-05 | 1.13 | 3.68E-13 | N |
| 10 | rs72837062 | 65271048 | 10q21.3 | A | 0.19 | 0.18 | 1.11 | 9.56E-10 | 0.19 | 0.18 | 1.09 | 2.52E-03 | 1.11 | 9.86E-12 | N |
| 10 | rs113772416 | 65309157 | 10q21.3 | A | 0.94 | 0.93 | 1.16 | 4.20E-08 | 0.93 | 0.93 | 1.12 | 1.22E-02 | 1.15 | 1.84E-09 | N |
| 10 | rs61855876 | 65357541 | 10q21.3 | T | 0.18 | 0.16 | 1.13 | 2.76E-12 | 0.18 | 0.16 | 1.21 | 5.03E-10 | 1.15 | 4.76E-20 | N |
| 10 | rs3858121 | 65399997 | 10q21.3 | C | 0.50 | 0.47 | 1.17 | 1.91E-30 | 0.51 | 0.47 | 1.16 | 9.37E-10 | 1.17 | 1.17E-38 | N |
| 10 | rs35311029 | 65445784 | 10q21.3 | T | 0.42 | 0.40 | 1.09 | 5.95E-10 | 0.42 | 0.40 | 1.09 | 5.25E-04 | 1.09 | 1.30E-12 | N |
| 10 | rs7097842 | 67245171 | 10q21.3 | G | 0.62 | 0.59 | 1.10 | 3.42E-12 | 0.61 | 0.59 | 1.10 | 4.47E-05 | 1.10 | 7.16E-16 | Y |
| 11 | rs6484426 | 29147101 | 11p14.1 | C | 0.14 | 0.13 | 1.15 | 7.22E-13 | 0.14 | 0.13 | 1.13 | 3.37E-04 | 1.14 | 1.22E-15 | Y |
| 11 | rs11218882 | 122771664 | 11q24.1 | T | 0.38 | 0.36 | 1.08 | 5.38E-08 | 0.38 | 0.37 | 1.06 | 1.21E-02 | 1.08 | 2.58E-09 | Y |
| 12 | rs56196860 | 2908330 | 12p13.33 | C | 0.98 | 0.97 | 2.04 | 1.06E-47 | 0.98 | 0.97 | 1.75 | 2.52E-12 | 1.96 | 2.44E-58 | Y |
| 12 | rs150948148 | 3077486 | 12p13.33 | A | 0.96 | 0.95 | 1.19 | 2.88E-07 | 0.96 | 0.95 | 1.25 | 1.84E-04 | 1.21 | 2.26E-10 | N |
| 12 | rs4149056 | 21331549 | 12p12.1 | C | 0.16 | 0.15 | 1.12 | 1.13E-10 | 0.17 | 0.15 | 1.17 | 5.97E-07 | 1.14 | 6.59E-16 | Y |
| 12 | rs11045856 | 21350689 | 12p12.1 | T | 0.77 | 0.76 | 1.08 | 3.35E-06 | 0.78 | 0.76 | 1.15 | 9.72E-07 | 1.09 | 1.01E-10 | N |
| 12 | rs28849840 | 50703384 | 12q13.12 | A | 0.36 | 0.35 | 1.08 | 4.89E-08 | 0.36 | 0.35 | 1.06 | 1.22E-02 | 1.08 | 2.17E-09 | Y |
| 12 | rs2250752 | 51106091 | 12q13.12 | C | 0.36 | 0.34 | 1.08 | 2.86E-08 | 0.36 | 0.34 | 1.07 | 7.06E-03 | 1.08 | 7.21E-10 | N |
| 12 | rs7484541 | 57714803 | 12q13.3 | A | 0.78 | 0.77 | 1.08 | 3.16E-06 | 0.79 | 0.77 | 1.11 | 1.42E-04 | 1.09 | 2.92E-09 | Y |
| 14 | rs28929474 | 94844947 | 14q32.13 | C | 0.99 | 0.98 | 1.52 | 8.83E-14 | 0.98 | 0.98 | 1.32 | 2.75E-03 | 1.47 | 1.76E-15 | Y |
| 15 | rs143875230 | 43278726 | 15q15.2 | A | 0.03 | 0.02 | 1.25 | 6.46E-08 | 0.03 | 0.02 | 1.24 | 3.69E-03 | 1.25 | 8.15E-10 | Y |
| 15 | rs754849914 | 43611767 | 15q15.3 | C | 0.14 | 0.13 | 1.10 | 9.91E-07 | 0.14 | 0.13 | 1.10 | 4.15E-03 | 1.10 | 1.23E-08 | N |
| 15 | rs150844304 | 43726625 | 15q15.3 | C | 0.03 | 0.02 | 1.31 | 3.21E-12 | 0.03 | 0.02 | 1.33 | 3.11E-05 | 1.32 | 3.40E-16 | N |
| 15 | rs8030169 | 44013177 | 15q15.3 | C | 0.13 | 0.12 | 1.10 | 2.97E-06 | 0.13 | 0.12 | 1.13 | 3.43E-04 | 1.11 | 4.89E-09 | N |
| 15 | rs139974673 | 44027885 | 15q15.3 | C | 0.03 | 0.02 | 1.34 | 2.77E-14 | 0.03 | 0.02 | 1.35 | 1.49E-05 | 1.35 | 1.41E-18 | N |
| 15 | rs138893177 | 44297617 | 15q15.3 | T | 0.03 | 0.02 | 1.35 | 1.89E-14 | 0.03 | 0.02 | 1.34 | 2.23E-05 | 1.35 | 1.48E-18 | N |
| 15 | rs148489550 | 44581461 | 15q15.3 | A | 0.03 | 0.02 | 1.28 | 5.49E-10 | 0.03 | 0.02 | 1.31 | 9.73E-05 | 1.29 | 2.38E-13 | N |
| 15 | rs4273010 | 44947434 | 15q21.1 | C | 0.03 | 0.02 | 1.29 | 4.91E-10 | 0.03 | 0.02 | 1.32 | 7.43E-05 | 1.30 | 1.69E-13 | N |
| 15 | rs77255942 | 53016517 | 15q21.3 | T | 0.04 | 0.03 | 1.19 | 2.58E-06 | 0.04 | 0.03 | 1.20 | 3.09E-03 | 1.19 | 2.79E-08 | Y |
| 15 | rs79391862 | 53739426 | 15q21.3 | C | 0.02 | 0.01 | 1.36 | 2.21E-08 | 0.02 | 0.01 | 1.47 | 1.73E-05 | 1.38 | 2.72E-12 | Y |
| 15 | rs5813220 | 63792758 | 15q22.31 | GT | 0.36 | 0.34 | 1.09 | 1.47E-09 | 0.35 | 0.34 | 1.07 | 3.81E-03 | 1.09 | 2.21E-11 | Y |
| 15 | rs8023580 | 96708291 | 15q26.2 | T | 0.74 | 0.72 | 1.13 | 5.46E-16 | 0.74 | 0.72 | 1.11 | 4.25E-05 | 1.13 | 1.37E-19 | Y |
| 16 | rs2764772 | 20060653 | 16p12.3 | T | 0.68 | 0.67 | 1.08 | 1.21E-07 | 0.69 | 0.67 | 1.12 | 6.44E-06 | 1.09 | 8.01E-12 | Y |
| 17 | rs6503017 | 7273147 | 17p13.1 | C | 0.31 | 0.29 | 1.14 | 3.19E-18 | 0.30 | 0.29 | 1.07 | 5.41E-03 | 1.12 | 4.22E-19 | N |
| 17 | rs7208523 | 7288228 | 17p13.1 | T | 0.13 | 0.11 | 1.17 | 1.68E-14 | 0.12 | 0.11 | 1.08 | 3.56E-02 | 1.15 | 1.19E-14 | N |
| 17 | rs35386490 | 7310006 | 17p13.1 | T | 0.79 | 0.76 | 1.22 | 6.67E-33 | 0.78 | 0.76 | 1.17 | 1.33E-08 | 1.20 | 1.08E-39 | N |
| 17 | rs77554485 | 7310754 | 17p13.1 | G | 0.04 | 0.03 | 1.21 | 2.77E-08 | 0.04 | 0.03 | 1.26 | 6.98E-05 | 1.23 | 1.04E-11 | N |
| 17 | rs74702014 | 7314543 | 17p13.1 | G | 0.96 | 0.96 | 1.20 | 2.73E-07 | 0.96 | 0.96 | 1.16 | 1.86E-02 | 1.19 | 1.91E-08 | N |
| 17 | rs76749877 | 7322087 | 17p13.1 | A | 0.09 | 0.08 | 1.12 | 1.71E-06 | 0.09 | 0.08 | 1.21 | 3.81E-06 | 1.14 | 1.14E-10 | N |
| 17 | rs12946520 | 7336371 | 17p13.1 | G | 0.41 | 0.35 | 1.32 | 6.75E-89 | 0.40 | 0.35 | 1.25 | 1.04E-19 | 1.30 | 6.80E-106 | Y |
| 17 | rs35490807 | 7368513 | 17p13.1 | C | 0.14 | 0.12 | 1.16 | 5.06E-13 | 0.13 | 0.12 | 1.14 | 3.20E-04 | 1.15 | 6.71E-16 | N |
| 17 | rs763671529 | 7423230 | 17p13.1 | C | 0.42 | 0.39 | 1.15 | 1.20E-24 | 0.41 | 0.39 | 1.14 | 3.67E-08 | 1.15 | 2.66E-31 | N |
| 17 | rs187079266 | 7438801 | 17p13.1 | A | 0.02 | 0.01 | 1.33 | 2.23E-07 | 0.02 | 0.01 | 1.33 | 1.86E-03 | 1.33 | 1.41E-09 | N |
| 17 | rs11078694 | 7448003 | 17p13.1 | T | 0.28 | 0.22 | 1.43 | 1.44E-119 | 0.27 | 0.21 | 1.40 | 2.79E-36 | 1.42 | 6.87E-154 | Y |
| 17 | rs4246413 | 7461469 | 17p13.1 | T | 0.06 | 0.05 | 1.28 | 4.43E-18 | 0.06 | 0.05 | 1.23 | 3.28E-05 | 1.27 | 8.84E-22 | N |
| 17 | rs183855978 | 7465735 | 17p13.1 | C | 0.03 | 0.02 | 1.34 | 1.29E-11 | 0.03 | 0.02 | 1.56 | 3.32E-10 | 1.39 | 2.30E-19 | Y |
| 17 | rs10468481 | 7474992 | 17p13.1 | A | 0.38 | 0.36 | 1.07 | 5.56E-07 | 0.38 | 0.36 | 1.09 | 6.85E-04 | 1.08 | 1.67E-09 | Y |
| 17 | rs9901675 | 7484812 | 17p13.1 | A | 0.06 | 0.05 | 1.21 | 4.15E-11 | 0.06 | 0.05 | 1.27 | 1.26E-06 | 1.22 | 4.54E-16 | N |
| 17 | rs12944954 | 7485131 | 17p13.1 | G | 0.04 | 0.02 | 1.98 | 4.08E-77 | 0.04 | 0.02 | 2.16 | 3.46E-34 | 2.02 | 4.54E-109 | Y |
| 17 | 17:7493904_AAGCCC_A | 7493904 | 17p13.1 | A | 0.02 | 0.02 | 1.58 | 4.63E-24 | 0.02 | 0.02 | 1.49 | 4.63E-07 | 1.55 | 1.34E-29 | Y |
| 17 | rs72829408 | 7523491 | 17p13.1 | C | 0.12 | 0.10 | 1.30 | 5.34E-37 | 0.13 | 0.10 | 1.35 | 6.85E-17 | 1.31 | 5.33E-52 | N |
| 17 | rs118098353 | 7531244 | 17p13.1 | C | 0.99 | 0.99 | 1.41 | 4.18E-07 | 0.99 | 0.99 | 1.48 | 8.29E-04 | 1.43 | 1.39E-09 | N |
| 17 | rs1799941 | 7533423 | 17p13.1 | G | 0.80 | 0.73 | 1.45 | 7.52E-111 | 0.79 | 0.73 | 1.40 | 6.56E-32 | 1.44 | 1.34E-140 | N |
| 17 | rs858517 | 7534271 | 17p13.1 | C | 0.06 | 0.05 | 1.39 | 1.71E-30 | 0.06 | 0.05 | 1.19 | 7.56E-04 | 1.33 | 3.48E-31 | N |
| 17 | rs6259 | 7536527 | 17p13.1 | G | 0.89 | 0.87 | 1.25 | 1.16E-24 | 0.89 | 0.87 | 1.26 | 3.40E-10 | 1.25 | 2.68E-33 | N |
| 17 | rs78496430 | 7565681 | 17p13.1 | A | 0.96 | 0.95 | 1.19 | 2.42E-07 | 0.96 | 0.95 | 1.21 | 9.90E-04 | 1.19 | 9.19E-10 | N |
| 17 | rs1641549 | 7574775 | 17p13.1 | T | 0.30 | 0.25 | 1.30 | 2.75E-69 | 0.29 | 0.25 | 1.30 | 4.14E-23 | 1.30 | 1.70E-90 | N |
| 17 | rs1642792 | 7576151 | 17p13.1 | A | 0.01 | 0.01 | 1.35 | 4.63E-07 | 0.01 | 0.01 | 1.35 | 4.02E-03 | 1.35 | 6.58E-09 | N |
| 17 | rs34289079 | 7593319 | 17p13.1 | C | 0.10 | 0.08 | 1.36 | 6.18E-41 | 0.09 | 0.08 | 1.30 | 1.17E-10 | 1.34 | 1.17E-49 | N |
| 17 | rs181975550 | 7595379 | 17p13.1 | C | 0.98 | 0.97 | 1.34 | 1.08E-10 | 0.98 | 0.97 | 1.48 | 5.91E-07 | 1.37 | 5.64E-16 | N |
| 17 | rs11870307 | 7617787 | 17p13.1 | A | 0.25 | 0.21 | 1.23 | 7.58E-38 | 0.24 | 0.21 | 1.20 | 7.98E-11 | 1.22 | 6.30E-47 | N |
| 17 | rs4968188 | 7629746 | 17p13.1 | C | 0.66 | 0.63 | 1.16 | 2.38E-25 | 0.66 | 0.62 | 1.20 | 2.30E-13 | 1.17 | 8.51E-37 | N |
| 17 | rs117387630 | 7651906 | 17p13.1 | T | 0.03 | 0.02 | 1.64 | 1.36E-30 | 0.03 | 0.02 | 1.65 | 4.57E-11 | 1.64 | 4.19E-40 | Y |
| 17 | rs117646332 | 7656668 | 17p13.1 | G | 0.95 | 0.94 | 1.19 | 6.39E-09 | 0.95 | 0.94 | 1.31 | 3.05E-07 | 1.22 | 3.16E-14 | N |
| 17 | 17:7686189_GA_G | 7686189 | 17p13.1 | GA | 0.06 | 0.05 | 1.21 | 3.84E-11 | 0.05 | 0.05 | 1.16 | 3.49E-03 | 1.20 | 6.54E-13 | N |
| 17 | rs2309810 | 7692510 | 17p13.1 | C | 0.42 | 0.41 | 1.09 | 2.06E-10 | 0.43 | 0.41 | 1.09 | 5.94E-04 | 1.09 | 4.62E-13 | N |
| 17 | rs62059712 | 7740170 | 17p13.1 | T | 0.93 | 0.92 | 1.16 | 1.80E-08 | 0.93 | 0.92 | 1.11 | 2.12E-02 | 1.15 | 1.74E-09 | N |
| 17 | rs62623385 | 7847837 | 17p13.1 | T | 0.04 | 0.03 | 1.28 | 4.07E-13 | 0.04 | 0.03 | 1.44 | 7.42E-10 | 1.32 | 9.38E-21 | N |
| 17 | rs56214516 | 43836953 | 17q21.31 | A | 0.82 | 0.80 | 1.09 | 3.49E-07 | 0.82 | 0.81 | 1.09 | 4.02E-03 | 1.09 | 4.85E-09 | N |
| 17 | rs62062271 | 44091988 | 17q21.31 | T | 0.79 | 0.77 | 1.09 | 3.53E-08 | 0.78 | 0.77 | 1.06 | 3.00E-02 | 1.09 | 4.64E-09 | Y |
| 17 | rs2696555 | 44348370 | 17q21.31 | A | 0.79 | 0.78 | 1.09 | 2.22E-07 | 0.79 | 0.78 | 1.07 | 2.01E-02 | 1.09 | 1.59E-08 | N |
| 17 | rs12941123 | 47259991 | 17q21.32 | C | 0.66 | 0.65 | 1.08 | 4.54E-07 | 0.66 | 0.65 | 1.06 | 1.64E-02 | 1.07 | 2.39E-08 | N |
| 17 | rs12950511 | 47320938 | 17q21.32 | T | 0.35 | 0.34 | 1.07 | 6.36E-07 | 0.36 | 0.33 | 1.12 | 8.10E-06 | 1.09 | 5.24E-11 | N |
| 17 | rs11655704 | 47448172 | 17q21.33 | T | 0.71 | 0.68 | 1.12 | 1.34E-15 | 0.71 | 0.68 | 1.14 | 1.35E-07 | 1.13 | 1.38E-21 | Y |
| 17 | 17:47457882_GAA_G | 47457882 | 17q21.33 | GAA | 0.92 | 0.91 | 1.16 | 1.04E-08 | 0.92 | 0.91 | 1.15 | 1.55E-03 | 1.15 | 6.10E-11 | N |
| 18 | rs600619 | 23662377 | 18q11.2 | G | 0.30 | 0.29 | 1.08 | 2.85E-07 | 0.31 | 0.29 | 1.08 | 4.76E-03 | 1.08 | 5.10E-09 | Y |
| 19 | rs55959020 | 17301935 | 19p13.11 | G | 0.97 | 0.97 | 1.21 | 2.46E-06 | 0.97 | 0.96 | 1.26 | 9.43E-04 | 1.22 | 1.20E-08 | N |
| 19 | rs35318830 | 46380325 | 19q13.32 | T | 0.90 | 0.89 | 1.13 | 2.07E-08 | 0.89 | 0.88 | 1.12 | 2.68E-03 | 1.13 | 2.05E-10 | Y |
| 22 | rs738409 | 44324727 | 22q13.31 | C | 0.80 | 0.78 | 1.09 | 5.42E-07 | 0.81 | 0.78 | 1.15 | 1.36E-06 | 1.10 | 1.59E-11 | Y |
| X | rs5933682 | 8783803 | Xp22.31 | A | 0.94 | 0.92 | 1.40 | 7.40E-17 | 0.95 | 0.93 | 1.49 | 5.43E-08 | 1.42 | 3.92E-23 | N |
| X | rs55994082 | 8784787 | Xp22.31 | G | 0.95 | 0.94 | 1.27 | 3.25E-08 | 0.95 | 0.94 | 1.36 | 3.75E-05 | 1.29 | 6.78E-12 | N |
| X | rs112183418 | 8848700 | Xp22.31 | C | 0.95 | 0.93 | 1.48 | 3.08E-19 | 0.96 | 0.93 | 1.60 | 1.49E-09 | 1.52 | 1.68E-27 | N |
| X | rs140143913 | 8900595 | Xp22.31 | A | 0.97 | 0.96 | 1.35 | 9.65E-09 | 0.97 | 0.96 | 1.57 | 2.07E-06 | 1.39 | 2.93E-13 | N |
| X | rs5933694 | 8902627 | Xp22.31 | A | 0.31 | 0.27 | 1.20 | 1.83E-18 | 0.31 | 0.27 | 1.23 | 1.78E-08 | 1.21 | 4.13E-25 | N |
| X | rs5934505 | 8913826 | Xp22.31 | T | 0.80 | 0.72 | 1.54 | 4.40E-76 | 0.81 | 0.72 | 1.66 | 1.64E-34 | 1.57 | 2.48E-108 | Y |
| X | rs1316470 | 8920762 | Xp22.31 | G | 0.88 | 0.86 | 1.22 | 1.14E-11 | 0.88 | 0.86 | 1.22 | 1.18E-04 | 1.22 | 5.17E-15 | N |
| X | rs5933699 | 8924923 | Xp22.31 | C | 0.55 | 0.52 | 1.14 | 2.00E-12 | 0.55 | 0.52 | 1.16 | 5.49E-06 | 1.15 | 6.14E-17 | N |
| X | rs137908282 | 8928551 | Xp22.31 | C | 0.95 | 0.93 | 1.38 | 1.00E-13 | 0.95 | 0.93 | 1.56 | 7.95E-09 | 1.42 | 1.63E-20 | N |
| X | rs6651991 | 56483572 | Xp11.21 | G | 0.81 | 0.79 | 1.16 | 2.45E-09 | 0.81 | 0.79 | 1.09 | 4.16E-02 | 1.14 | 4.62E-10 | Y |
| X | rs4607760 | 56821840 | Xp11.21 | A | 0.82 | 0.80 | 1.17 | 7.99E-11 | 0.82 | 0.80 | 1.10 | 3.31E-02 | 1.15 | 2.03E-11 | N |
| X | rs56202849 | 57163183 | Xp11.21 | G | 0.82 | 0.80 | 1.17 | 4.59E-10 | 0.82 | 0.80 | 1.10 | 2.19E-02 | 1.15 | 6.25E-11 | N |
| X | rs141955903 | 61973907 | Xq11.1 | C | 0.02 | 0.02 | 1.36 | 3.55E-06 | 0.02 | 0.02 | 1.46 | 6.67E-04 | 1.39 | 9.15E-09 | N |
| X | rs149312565 | 63295055 | Xq11.2 | C | 0.02 | 0.01 | 1.42 | 2.26E-06 | 0.02 | 0.01 | 1.47 | 2.82E-03 | 1.44 | 2.22E-08 | N |
| X | rs187365633 | 63332756 | Xq11.2 | T | 0.10 | 0.09 | 1.17 | 1.74E-06 | 0.10 | 0.09 | 1.17 | 5.58E-03 | 1.17 | 3.09E-08 | N |
| X | X:63722761_TC_T | 63722761 | Xq11.2 | T | 0.02 | 0.01 | 1.42 | 4.51E-06 | 0.02 | 0.01 | 1.57 | 4.04E-04 | 1.46 | 8.87E-09 | N |
| X | X:65604623_AC_A | 65604623 | Xq12 | AC | 0.21 | 0.19 | 1.14 | 3.55E-08 | 0.21 | 0.19 | 1.18 | 4.60E-05 | 1.15 | 1.13E-11 | N |
| X | rs149920923 | 65719169 | Xq12 | T | 0.02 | 0.01 | 1.54 | 4.08E-08 | 0.01 | 0.01 | 1.33 | 4.81E-02 | 1.49 | 8.72E-09 | N |
| X | rs545399 | 65878187 | Xq12 | G | 0.21 | 0.19 | 1.17 | 5.27E-11 | 0.21 | 0.19 | 1.22 | 1.38E-06 | 1.18 | 1.15E-15 | N |
| X | rs141086308 | 65897736 | Xq12 | C | 0.99 | 0.98 | 1.48 | 2.46E-06 | 0.99 | 0.98 | 2.06 | 8.74E-06 | 1.60 | 2.37E-10 | Y |
| X | rs149173774 | 66122885 | Xq12 | A | 0.02 | 0.01 | 1.66 | 1.86E-12 | 0.02 | 0.01 | 1.30 | 4.82E-02 | 1.56 | 1.81E-12 | N |
| X | rs193285839 | 66165277 | Xq12 | A | 0.99 | 0.98 | 1.65 | 8.56E-08 | 0.99 | 0.98 | 2.60 | 4.55E-07 | 1.83 | 5.24E-13 | N |
| X | rs78907332 | 66180874 | Xq12 | T | 0.16 | 0.14 | 1.19 | 3.54E-11 | 0.16 | 0.14 | 1.22 | 1.12E-05 | 1.20 | 4.53E-15 | N |
| X | rs7472818 | 66473124 | Xq12 | T | 0.02 | 0.01 | 1.69 | 6.39E-13 | 0.02 | 0.01 | 1.32 | 3.78E-02 | 1.59 | 5.23E-13 | N |
| X | rs139106020 | 66489579 | Xq12 | A | 0.09 | 0.08 | 1.25 | 5.77E-11 | 0.09 | 0.07 | 1.28 | 3.56E-05 | 1.25 | 1.56E-14 | N |
| X | rs112482463 | 66580676 | Xq12 | A | 0.86 | 0.84 | 1.19 | 7.16E-11 | 0.85 | 0.83 | 1.20 | 1.21E-04 | 1.19 | 7.15E-14 | N |
| X | rs146415516 | 66607743 | Xq12 | C | 0.99 | 0.98 | 1.69 | 7.86E-09 | 0.99 | 0.98 | 2.59 | 2.25E-07 | 1.87 | 2.27E-14 | N |
| X | rs5919411 | 66918713 | Xq12 | A | 0.09 | 0.08 | 1.25 | 2.55E-11 | 0.09 | 0.08 | 1.32 | 1.46E-06 | 1.26 | 4.26E-16 | N |
| X | rs148526654 | 67025293 | Xq12 | A | 0.99 | 0.98 | 1.80 | 6.74E-10 | 0.99 | 0.98 | 2.53 | 4.40E-07 | 1.95 | 2.11E-15 | N |
| X | rs142188276 | 67059111 | Xq12 | C | 0.87 | 0.86 | 1.14 | 7.33E-06 | 0.88 | 0.86 | 1.18 | 7.80E-04 | 1.15 | 2.24E-08 | N |
| X | rs140290317 | 67135247 | Xq12 | A | 0.02 | 0.01 | 1.64 | 1.40E-11 | 0.02 | 0.01 | 1.33 | 3.25E-02 | 1.56 | 6.43E-12 | N |
| X | rs144254006 | 67279380 | Xq12 | C | 0.99 | 0.99 | 1.66 | 7.94E-06 | 0.99 | 0.99 | 2.43 | 6.09E-05 | 1.82 | 2.78E-09 | N |
| X | rs7052964 | 67403723 | Xq12 | G | 0.21 | 0.18 | 1.22 | 3.01E-16 | 0.20 | 0.18 | 1.18 | 9.85E-05 | 1.21 | 1.76E-19 | Y |
| X | rs140555778 | 67415777 | Xq12 | A | 0.05 | 0.04 | 1.30 | 7.34E-09 | 0.05 | 0.04 | 1.21 | 1.71E-02 | 1.27 | 6.00E-10 | N |
| X | rs5942977 | 109833905 | Xq23 | G | 0.66 | 0.60 | 1.36 | 1.87E-52 | 0.64 | 0.60 | 1.26 | 1.92E-11 | 1.33 | 1.76E-61 | Y |
| X | rs5943061 | 109987387 | Xq23 | A | 0.77 | 0.75 | 1.14 | 1.73E-08 | 0.77 | 0.75 | 1.12 | 4.55E-03 | 1.13 | 3.35E-10 | N |
LD = linkage disequilibrium; N = no; OR = odds ratio; SNP = single nucleotide polymorphism; T = testosterone; Y = yes.