Table 4.
Outcome | Number of trials (evaluated) | Intervention | Control | Results | Relative risk (95% CI) | Quality of evidence |
---|---|---|---|---|---|---|
% (n/N) or mean change | % (n/N) or mean change | Absolute risk difference (95% CI) | ||||
Responders, based on IPSS reduction of ≥8 points | 1 (30) | 87 (13/15) | 100 (15/15) | Similar between groups | 0.9 (0.7 to 1.1) | Lowa, b |
–13.3% (–33.1 to 6.4) | ||||||
IPSS, mean change from baseline: long-term follow-up (>12 mo) | 1 (107) | –15.6 points | –16.3 points | Similar between groups | Moderatea | |
MD –0.7 (–1.3 to 2.7) | ||||||
IPSS-QoL, mean change from baseline: long-term follow-up (>12 mo) | 1 (107) | –3.2 points | –3.2 points | Similar between groups | Moderatea | |
MD –0.0 (–0.0 to 0.0) | ||||||
Need for reoperation | 2 (144) | 10 (7/72) | 3 (2/72) | 7% (–0.9% to 14.8) | 2.9 (0.7–11.9) | Very lowa, c |
Transfusion | 2 (144) | 0 (0/72) | 3 (2/72) | –2.8% (–7.4 to 1.8) | 0.2 (0.01–4.1) | Very lowa, c |
Urinary incontinence | 2 (129) | 0 (0/63) | 11 (7/66) | Greater with TURP | 0.1 (0.02–0.99) | Lowa, b |
–10.6% (–18.5 to –2.8) |
CI = confidence intervals; IPSS = International Prostate Symptom Score; MD = mean difference; QoL = quality of life; TURP = transurethral resection of the prostate.
Downgraded based on the following:
Risk of bias (moderate).
Imprecision.
Very wide confidence interval and few events.