Table 1.
Baseline characteristics by trial
| Characteristic | WATER (n = 117) |
WATER II (n = 101) |
p value |
|---|---|---|---|
| Mean age, yr (SD) | 65.9 (7.3) | 67.5 (6.6) | 0.0854 |
| Mean body mass index, kg/m2 (SD) | 28.4 (4.1) | 28.3 (4.1) | 0.8231 |
| Mean prostate-specific antigen, g/dl (SD) | 3.7 (3) | 7.1 (5.9) | <0.0001 |
| Mean prostate size, cm3 (SD) [range] | 54.1 (16.3) [25–80] | 107.4 (20.2) [80–150] | <0.0001 |
| Median lobe present, n (%) | 58 (50) | 73 (72) | 0.0044 |
| Intravesical component | 42/58 (72) | 69/73 (95) | |
| Use of catheter within 45 d before consent, n (%) | – a | 16 (16) | – |
| Mean IPSS (SD) | 22.9 (6) | 23.2 (6.3) | 0.6933 |
| Mean IPSS QOL (SD) | 4.8 (1.1) | 4.6 (1) | 0.1805 |
IPSS = International Prostate Symptom Score; QOL = quality of life domain; SD = standard deviation.
a
Patients reporting urinary catheter use in the 14 d before evaluation or with history of intermittent self-catheterization were excluded from WATER.