Fig. 1.

Percentage change in PSMA SUV_max in biopsied metastases after [¹⁷⁷Lu]-PSMA-617 therapy for individual patients. Blue bars = lesion responded; brown bars = lesion stable; yellow bars = lesion progressed according to Positron Emission Tomography Response Criteria in Solid Tumors. The x-axis shows the individual patients with the number above the colums describing the PSMA protein expression assessed by immunohistochemistry of the investigated lesion at baseline.

PSMA = prostate-specific membrane antigen; SUV_max = maximum standardized uptake value on [⁶⁸Ga]-PSMA positron emission tomography imaging.